Firefly to Karen Sisco
5 connections
Firefly
Angel
Weyland-Utani is a client of Angel's Wolfram & Hart and also the company that made some of the weapons used by Firefly's Malcolm Reynolds in the Battle of Serenity
Buffy the Vampire Slayer
Angel was a spin-off of Buffy the Vampire Slayer.
The X-Files
The X-Files? Cigarette Smoking Man and Buffy the Vampire Slayer's Spike both smoked Morley cigarettes.
Justified
Morleys
Karen Sisco
Karen Sisco (under her new married name) appears as an Assistant Director working with Raylan Given on Justified.